Conversion of deoxypodophyllotoxin to podophyllotoxin-related compounds by microbes.

Biotransformation of podophyllotoxin to picropodophyllin by microbes.

Biotransformation of podophyllotoxin (PT) by several microbial species has been investigated. Among the fungi tested, it was found that Penicillium strains can isomerize PT to picropodophyllin (PPT) in 8% yield and other strains also transform the substrate into the same product but with lower yield.

High yield of podophyllotoxin from leaves of Podophyllum peltatum by in situ conversion of podophyllotoxin 4- O-beta-D-glucopyranoside.

Rehydration of powdered tissues of Podophyllum peltatum L. prior to extraction with an organic solvent allows endogenous beta-glucosidases to hydrolyze lignan 4-O-beta-D-glucosides in situ and increase the yield of podophyllotoxin. Aqueous extraction of rhizomes and leaves of P. peltatum yielded 4- to 10-fold greater quantities of podophyllotoxin than the traditional ethanolic extraction. Most ...

Editorial: Bioactive Compounds from Microbes

Editorial on the Research Topic Bioactive Compounds from Microbes Microorganisms are ubiquitous and essentially interact with all the other organisms present in the biosphere, sometimes creating a network of signals that constitutes the basis for life on the Earth. Clarifying the nature of these molecular signals, their targets and the pathways underlying their production, constitutes the essen...

Biodegradation of Phenolic Compounds by Using Halotolerant Microbes

1,4-bis(triphenyl phosphonium)butane peroxodisulfate: conversion of alkyl benzenes to carbonyl compounds

1,4-bis(triphenyl phosphonium)butane peroxodisulfate(BTPPBPDS) were synthesized by treating 1,4-bis(triphenyl phosphonium)butane dibromide and potassium peroxydisulfate in aqueous solution.This was used mild and efficient reagent for oxidation of alkyl benzenes to their corresponding carbonyl compounds in very good to high yields.